IL-15 anticorps (AA 70-162)
Aperçu rapide pour IL-15 anticorps (AA 70-162) (ABIN7602347)
Antigène
Voir toutes IL-15 (IL15) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 70-162
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Fonction
- Anti-IL15 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-IL15 Antibody Picoband® (ABIN7602347). Tested in ELISA, Flow Cytometry, IHC applications. This antibody reacts with Human, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human IL15 recombinant protein (Position: D70-S162).
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Isotype
- IgG
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Indications d'application
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Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Anderson, D. M., Johnson, L., Glaccum, M. B., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Valentine, V., Kirstein, M. N., Shapiro, D. N., Morris, S. W., Grabstein, K., Cosman, D. Chromosomal assignment and genomic structure of IL15. Genomics 25: 701-706, 1995. 2. Conti F, Frappier J, Dharancy S, Chereau C, Houssin D, Weill B, Calmus Y. Interleukin-15 production during liver allograft rejection in humans. Transplantation. 2003 Jul 15,76(1):210-6. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IL-15 (IL15) (Interleukin 15 (IL15))
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Autre désignation
- IL15
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Sujet
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Synonyms: GTP-binding nuclear protein Ran,Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein,RAN,ARA24,OK/SW-cl.81,
Tissue Specificity: Expressed in a variety of tissues. .
Background: Interleukin (IL)-15 is a cytokine with the ability to stimulate the proliferation activity of Th1 and/or Th2 lymphocytes. This gene is mapped to human chromosome 4q31 by fluorescence in situ hybridization. IL-15 is a novel cytokine whose effects on T-cell activation and proliferation are similar to those of interleukin-2 (IL-2), presumably because IL-15 utilizes the beta and gamma chains of the IL-2 receptor. IL-15 can play a role in the initiation and outcome of acute and chronic rejection. Anti-IL-15 therapy in combination with classic immunosuppression therapy might be beneficial in the prevention of acute, and especially chronic, allograft rejection.
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Poids moléculaire
- 60 kDa
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ID gène
- 3600
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UniProt
- P40933
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Pathways
- Signalistation JAK/STAT, Glycosaminoglycan Metabolic Process
Antigène
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